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Article

Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.

Neuro-oncology - 1 Aug 2009

Jun Peter, Hong Chibo, Lal Anita, Wong Judith M, McDermott Michael W, Bollen Andrew W, Plass Christoph, Held William A, Smiraglia Dominic J, Costello Joseph F

Abstract excerpt

Both genetic and epigenetic mechanisms contribute to meningioma development by altering gene expression and protein function. To determine the relative contribution of each mechanism to meningioma development, we used an integrative approach measuring copy number and DNA methylation changes genom...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19001526
DOI: 10.1215/15228517-2008-096
PMCID: PMC2743221

Genes

WNK2
WNK1
WNK3
WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19001526-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.PMID 19001526Read ↗

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