Article
Molecular genetics of meningiomas.
Handbook of clinical neurology - 1 Jan 2020
Youngblood Mark W, Günel Murat
Abstract excerpt
Comprehensive genomic studies of meningioma have offered important insights about the molecular mechanisms underlying this common brain tumor. The use of next-generation sequencing techniques has identified driver mutations in approximately 80% of benign sporadic lesions, as well as epigenetic, regulatory, and copy number events that are associated with formation and disease progression. The events described to...
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