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Article

TP53 mutational analysis supports monoclonal origin of biphasic sarcomatoid urothelial carcinoma (carcinosarcoma) of the urinary bladder.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2009

Armstrong Andrew B, Wang Mingsheng, Eble John N, MacLennan Gregory T, Montironi Rodolfo, Tan Puay-Hoon, Lopez-Beltran Antonio, Zhang Shaobo, Baldridge Lee Ann, Spartz Helena, Cheng Liang

Abstract excerpt

Sarcomatoid urothelial carcinoma of the urinary bladder is an uncommon neoplasm with biphasic morphology exhibiting both epithelial and sarcomatoid components. Whether this tumor arises from a single cancer stem cell with subsequent differentiation or represents collision of the progeny of two separate cancer stem cells is a matter of controversy. To clarify its clonal origin, we analyzed the TP53 mutation status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18997737
DOI: 10.1038/modpathol.2008.176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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