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Article

Monoclonal Origins of Malignant Mixed Tumors (Carcinosarcomas)

1 Mar 1996

Abstract excerpt

Malignant mixed tumors (carcinosarcomas) are examples of unusual neoplasms whose occurrences have been observed in increasingly diverse sites but whose pathogenesis remains a complete mystery. Two antithetical hypotheses that have been advanced to explain the histogenesis of these tumors include the convergence hypothesis, which proposes an origin from two or more stem cells (multiclonal hypothesis), and the...

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PMID: 8772780
DOI: 10.1097/00000478-199603000-00003

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