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Article

Löfgren's syndrome: human leukocyte antigen strongly influences the disease course.

American journal of respiratory and critical care medicine - 15 Feb 2009

Grunewald Johan, Eklund Anders

Abstract excerpt

RATIONALE: Sarcoidosis may consist of a number of distinct disease entities, one of which could be Löfgren's syndrome. Patients with Löfgren's syndrome have an acute onset of erythema nodosum (EN) and/or periarticular inflammation or arthritis of the ankles, with bilateral hilar lymphadenopathy (and in some cases parenchymal infiltrates) and usually fever. There is a known association between HLA-DRB1*03 and...

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Identifiers

PMID: 18996998
DOI: 10.1164/rccm.200807-1082OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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