Article
HLA-alleles associated with increased risk for extra-pulmonary involvement in sarcoidosis.
Tissue antigens - 1 Apr 2014
Darlington P, Gabrielsen A, Sörensson P, Tallstedt L, Padyukov L, Eklund A, Grunewald J
Abstract excerpt
Genetic factors influence the risk for disease as well as the clinical picture seen in sarcoidosis and especially the genes localized to the human leukocyte antigen (HLA) region on chromosome 6 are of importance. The aim of this study was to further investigate associations between HLA-DRB1 alleles and the risk for extra-pulmonary manifestations (EPMs), i.e. engagement of the skin, superficial lymph nodes, eyes,...
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