Article
Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients.
Respiratory research - 26 Feb 2010
Grunewald Johan, Brynedal Boel, Darlington Pernilla, Nisell Magnus, Cederlund Kerstin, Hillert Jan, Eklund Anders
Abstract excerpt
BACKGROUND: A strong genetic influence by the MHC class II region has been reported in sarcoidosis, however in many studies with different results. This may possibly be caused by actual differences between distinct ethnic groups, too small sample sizes, or because of lack of accurate clinical subgrouping. SUBJECTS AND METHODS: In this study we HLA typed a large patient population (n = 754) recruited from one...
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