Article
Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva.
European journal of cell biology - 1 Mar 2009
Gangishetti Umesh, Breitenbach Sophie, Zander Mareike, Saheb Shaik Khaleelulla, Müller Ursula, Schwarz Heinz, Moussian Bernard
Abstract excerpt
Chitin is an essential constituent of the insect exoskeleton, the cuticle, which is an extracellular matrix (ECM) covering the animal. It is produced by the glycosyltransferase chitin synthase at the apical plasma membrane of epidermal and tracheal cells. To fulfil its role in cuticle elasticity and stiffness it associates with proteins, thereby adopting a stereotypic arrangement of helicoidally stacked sheets,...
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