Article
Hormonal regulation of mummy is needed for apical extracellular matrix formation and epithelial morphogenesis in Drosophila.
Development (Cambridge, England) - 1 Jan 2006
Tonning Anna, Helms Sigrun, Schwarz Heinz, Uv Anne E, Moussian Bernard
Abstract excerpt
Many epithelia produce apical extracellular matrices (aECM) that are crucial for organ morphogenesis or physiology. Apical ECM formation relies on coordinated synthesis and modification of constituting components, to enable their subcellular targeting and extracellular assembly into functional matrices. The exoskeleton of Drosophila, the cuticle, is a stratified aECM containing ordered chitin polysaccharide...
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