Article
Deciphering the genetic programme triggering timely and spatially-regulated chitin deposition.
PLoS genetics - 1 Jan 2015
Moussian Bernard, Letizia Annalisa, Martínez-Corrales Guillermo, Rotstein Bárbara, Casali Andreu, Llimargas Marta
Abstract excerpt
Organ and tissue formation requires a finely tuned temporal and spatial regulation of differentiation programmes. This is necessary to balance sufficient plasticity to undergo morphogenesis with the acquisition of the mature traits needed for physiological activity. Here we addressed this issue by analysing the deposition of the chitinous extracellular matrix of Drosophila, an essential element of the cuticle...
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