Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine.

Respiratory medicine - 1 Mar 2009

Moradi Mandana, Mojtahedzadeh Mojtaba, Mandegari Ali, Soltan-Sharifi Mohammad Sadegh, Najafi Atabak, Khajavi Mohammad Reza, Hajibabayee Molook, Ghahremani Mohammad Hossein

Abstract excerpt

Oxidative stress has a proven role in pathophysiology of acute respiratory distress syndrome. The antioxidant drugs, especially N-acetylcysteine (NAC) have been used for years to overcome oxidative stress effects in patients. In the present study we have investigated the effects of NAC treatment (IV NAC in 150mg/kg at the first day followed by 50mg/kg/day for three days) on 27 ICU patients with ALI/ARDS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcysteine
Share to Acute Lung Injury

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antioxidants

Share to Chi-Square Distribution

Share to Drug Administration Schedule

Share to Glutathione Transferase

Share to Respiratory Distress Syndrome

Share to Single-Blind Method

Source

Identifiers

PMID: 18993042
DOI: 10.1016/j.rmed.2008.09.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine.PMID 18993042Read ↗

Machine learning algorithms and computational validation of single-nucleotide polymorphisms of antioxidant enzymes and oxidative stress markers in neonates.Semantic proximity Read ↗

Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter.Semantic proximity Read ↗

A novel approach to study oxidative stress in neonatal respiratory distress syndromeSemantic proximity Read ↗

Genetic polymorphisms of glutathione S-transferase M1 and T1, and evaluation of oxidative stress in patients with non-small cell lung cancer.Semantic proximity Read ↗

Relationship between oxidative stress, glutathione S-transferase polymorphisms and hydroxyurea treatment in sickle cell anemia.Semantic proximity Read ↗

Angiotensin-converting enzyme polymorphism affects outcome of local Chinese with acute lung injury.Semantic proximity Read ↗

Glutathione S-transferases related to P. aeruginosa lung infection in cystic fibrosis children: preliminary study.Semantic proximity Read ↗

The impact of the PAI-1 4G/5G polymorphism on the outcome of patients with ALI/ARDS.Semantic proximity Read ↗

Heme oxygenase 1 polymorphisms and plasma concentrations in critically ill patients.Semantic proximity Read ↗

Plasma antioxidants are associated with impaired lung function and COPD exacerbations in smokers.Semantic proximity Read ↗

Association of the superoxide dismutase (V16A) and catalase (C262T) genetic polymorphisms with the clinical outcome of patients with acute paraquat intoxication.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.