Article
Genetic polymorphisms of glutathione S-transferase M1 and T1, and evaluation of oxidative stress in patients with non-small cell lung cancer.
European journal of medical research - 4 Dec 2014
Zhang Hongyan, Wu Xuwei, Xiao Yi, Chen Mei, Li Zhidong, Wei Xing, Tang Kaifa
Abstract excerpt
BACKGROUND: Our objective is to investigate the genetic polymorphisms of the glutathione S-transferase M1 and T1 genes (GSTM1 and GSTT1) and evaluate oxidative damage in patients with non-small lung cancer (N-SCLC). METHODS: One hundred and ten patients with N-SCLC and 100 controls are included in this case-control study. Multiplex polymerase chain reaction (PCR) analyses were used to identify the genotypes. The...
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