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Article

Primary sclerosing cholangitis in childhood is associated with abnormalities in cystic fibrosis-mediated chloride channel function.

The Journal of pediatrics - 1 Sept 2007

Pall Harpreet, Zielenski Julian, Jonas Maureen M, DaSilva Deborah A, Potvin Kimberly M, Yuan Xiao-Wei, Huang Qiuju, Freedman Steven D

Abstract excerpt

OBJECTIVE: To determine whether primary sclerosing cholangitis (PSC) in childhood is associated with abnormalities in cystic fibrosis transmembrane conductance regulator (CFTR). STUDY DESIGN: Subjects with PSC diagnosed in childhood (n = 20) were recruited from Children's Hospital. Subjects had testing with sweat chloride concentration, nasal transmembrane potential difference, and extensive genetic analysis of...

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Share to Cholangitis, Sclerosing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17719933
DOI: 10.1016/j.jpeds.2007.03.062

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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