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Article

Helicobacter pylori mutants defective in the clpP ATP-dependant protease and the chaperone clpA display reduced macrophage and murine survival.

Microbial pathogenesis - 1 Jan 2009

Loughlin Michael F, Arandhara Victoria, Okolie Charles, Aldsworth Timothy G, Jenks Peter J

Abstract excerpt

The ATP-dependent caseinolytic proteases (Clp) are important in resistance against environmental stresses, antibiotic treatments and host immune defences for a number of pathogenic bacteria. ClpP is the proteolytic subunit, whilst ClpA acts both as a chaperone and as an ATPase driving the degrada...

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Source

Identifiers

PMID: 18992803
DOI: 10.1016/j.micpath.2008.10.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18992803-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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