Hsp100 Molecular Chaperone ClpB and Its Role in Virulence of Bacterial Pathogens

doi:10.3390/ijms22105319

Article

Hsp100 Molecular Chaperone ClpB and Its Role in Virulence of Bacterial Pathogens

18 May 2021

Abstract excerpt

This review focuses on the molecular chaperone ClpB that belongs to the Hsp100/Clp subfamily of the AAA+ ATPases and its biological function in selected bacterial pathogens, causing a variety of human infectious diseases, including zoonoses. It has been established that ClpB disaggregates and reactivates aggregated cellular proteins. It has been postulated that ClpB's protein disaggregation activity supports the...

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