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Article

The Transcriptional Repressor Protein NsrR Senses Nitric Oxide Directly via a [2Fe-2S] Cluster

6 Nov 2008

Abstract excerpt

The regulatory protein NsrR, a member of the Rrf2 family of transcription repressors, is specifically dedicated to sensing nitric oxide (NO) in a variety of pathogenic and non-pathogenic bacteria. It has been proposed that NO directly modulates NsrR activity by interacting with a predicted [Fe-S] cluster in the NsrR protein, but no experimental evidence has been published to support this hypothesis. Here we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18989365
DOI: 10.1371/journal.pone.0003623

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