Article
Heme and nitric oxide binding by the transcriptional regulator DnrF from the marine bacterium Dinoroseobacter shibae increases napD promoter affinity.
The Journal of biological chemistry - 15 Sept 2017
Ebert Matthias, Schweyen Peter, Bröring Martin, Laass Sebastian, Härtig Elisabeth, Jahn Dieter
Abstract excerpt
Under oxygen-limiting conditions, the marine bacterium Dinoroseobacter shibae DFL12T generates energy via denitrification, a respiratory process in which nitric oxide (NO) is an intermediate. Accumulation of NO may cause cytotoxic effects. The response to this nitrosative (NO-triggered) stress is controlled by the Crp/Fnr-type transcriptional regulator DnrF. We analyzed the response to NO and the mechanism of NO...
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