Article
Pharmacogenetics influence treatment efficacy in childhood acute lymphoblastic leukemia.
Journal of pediatric hematology/oncology - 1 Nov 2008
Davidsen Marie Louise, Dalhoff Kim, Schmiegelow Kjeld
Abstract excerpt
Pharmacogenetics covers the genetic variation affecting pharmacokinetics and pharmacodynamics, and their influence on drug-response phenotypes. The genetic variation includes an estimated 15 million single nucleotide polymorphisms (SNPs) and is a key determinator for the interindividual differenc...
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