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Article

Thiopurine S-methyltransferase pharmacogenetics in childhood acute lymphoblastic leukemia.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Yang Jun J, Bhojwani Deepa

Abstract excerpt

Pharmacogenetics is the growing field of study of genetic variations underlying interindividual differences in drug response. Inherited polymorphisms in genes coding for drug-metabolizing enzymes, transporters, and targets influence toxicity as well as efficacy associated with the medication. Thiopurines are agents widely used in hematologic malignancies, transplantation, and chronic inflammatory conditions....

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Share to TPMT gene
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Share to Inactivation, Metabolic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methyltransferases

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Share to Polymorphism, Genetic

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 23666706
DOI: 10.1007/978-1-62703-357-2_20

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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