Article
Pharmacogenomics in cancer treatment defining genetic bases for inter-individual differences in responses to chemotherapy.
Current opinion in pediatrics - 1 Feb 2007
Ansari Marc, Krajinovic Maja
Abstract excerpt
PURPOSE OF REVIEW: Pharmacogenomics is evolving rapidly due to the expansion of genomics and proteomics, the emerging technologies, knowledge of the molecular basis of neoplasms and of drug pathways. This article will give an update on the genetic basis of variable therapeutic responses to anticancer agents in children. RECENT FINDINGS: The majority of recent findings concern the pharmacogenetics of key...
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