Article
EGFR mutations are more frequent in well-differentiated than in poor-differentiated lung adenocarcinomas.
Pathology oncology research : POR - 1 Dec 2008
Liu Yan, Xu Mei Lin, Zhong Hao Hao, Heng Wan Jie, Wu Bing Quan
Abstract excerpt
Somatic mutations in epidermal growth factor receptor (EGFR) tyrosine kinase domain, particularly deletions in exon 19 and point mutation in exon 21, are associated with clinical outcome in patients with lung adenocarcinoma, suggesting that EGFR mutation would have an important role in clinical d...
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