Article
Histopathologic characteristics of pulmonary adenocarcinomas with and without EGFR mutation.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Sept 2005
Chantranuwat Chavit, Sriuranpong Virote, Huapai Nusara, Chalermchai Thep, Leungtaweeboon Kittichai, Voravud Narin, Mutirangura Apiwat
Abstract excerpt
UNLABELLED: EGFR mutation played crucial role for responsiveness of non-small cell lung cancers to EGFR tyrosine kinase inhibitors. Almost the mutations were present in adenocarcinomas. Few had studied on histopathologic correlation with EGFR mutation in pulmonary adenocarcinomas. To obtain better view on pathobiology of pulmonary adenocarcinomas, we correlated exons 19 and 21 mutations with various...
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