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A comparison of affected and unaffected relatives of patients with bipolar disorder using proton magnetic resonance spectroscopy

1 Nov 2008

Abstract excerpt

OBJECTIVE: Bipolar disorders have a strong genetic underpinning. Little is known about biological predispositions that convey vulnerability for the illness. We searched for biological vulnerability markers using proton magnetic resonance spectroscopy (MRS) in both affected and unaffected participants at high genetic risk for bipolar disorder. METHODS: We recruited high-risk participants aged 15-30 years from...

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PMID: 18982176
DOI: 10.1139/jpn.0851

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