Article
Altered lipid metabolism in Drosophila model of Huntington's disease.
Scientific reports - 10 Aug 2016
Aditi Kumari, Shakarad Mallikarjun N, Agrawal Namita
Abstract excerpt
Huntington's disease (HD) is late-onset, progressive neurodegenerative disorder caused by expansion of polyglutamine (polyQ) repeat within Huntingtin (Htt) protein. In HD patients, energy-related manifestations such as modulation of weight during entire course of disease with energy deficit at terminal stage have been reported, however, underlying reason remains elusive till date. Lipids, carbohydrate and protein...
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