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Article

Ig beta deficiency in humans.

Current opinion in allergy and clinical immunology - 1 Dec 2008

Lougaris Vassilios, Ferrari Simona, Plebani Alessandro

Abstract excerpt

PURPOSE OF REVIEW: To describe novel immunological and molecular findings regarding early B cell development arrest resulting in autosomal recessive agammaglobulinemia. RECENT FINDINGS: Recently two different groups identified mutations in Ig beta, a component of the pre-B cell receptor, responsible for agammaglobulinemia in humans. These are the first two patients ever described with mutations in Ig beta....

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PMID: 18978465
DOI: 10.1097/ACI.0b013e328314b621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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