Article
A genomic distance based on MUM indicates discontinuity between most bacterial species and genera.
Journal of bacteriology - 1 Jan 2009
Deloger Marc, El Karoui Meriem, Petit Marie-Agnès
Abstract excerpt
The fundamental unit of biological diversity is the species. However, a remarkable extent of intraspecies diversity in bacteria was discovered by genome sequencing, and it reveals the need to develop clear criteria to group strains within a species. Two main types of analyses used to quantify intraspecies variation at the genome level are the average nucleotide identity (ANI), which detects the DNA conservation...
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