Article
Intraspecies variation in bacterial genomes: the need for a species genome concept.
Trends in microbiology - 1 Sept 2000
Lan R, Reeves P R
Abstract excerpt
Bacterial populations are clonal. Their evolution involves not only divergence between orthologous genes but also gain of genes from other clones or species, which has only recently been widely appreciated through macrorestriction mapping, genomic subtraction and complete genome sequencing. Genes can also be lost in response to selection or by random mutation after becoming redundant. The bacterial genome is a...
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