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Article

Genomic insights that advance the species definition for prokaryotes.

Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 2005

Konstantinidis Konstantinos T, Tiedje James M

Abstract excerpt

To help advance the species definition for prokaryotes, we have compared the gene content of 70 closely related and fully sequenced bacterial genomes to identify whether species boundaries exist, and to determine the role of the organism's ecology on its shared gene content. We found the average nucleotide identity (ANI) of the shared genes between two strains to be a robust means to compare genetic relatedness...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15701695
DOI: 10.1073/pnas.0409727102
PMCID: PMC549018

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Source receipt: pubmed, retrieved 7 Sept 2026.

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