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Article

Mutagenesis of region 4 of sigma 28 from Chlamydia trachomatis defines determinants for protein-protein and protein-DNA interactions.

Journal of bacteriology - 1 Jan 2009

Hua Ziyu, Rao Xiancai, Feng Xiaogeng, Luo Xudong, Liang Yanmei, Shen Li

Abstract excerpt

Transcription factor sigma(28) in Chlamydia trachomatis (sigma(28)(Ct)) plays a role in the regulation of genes that are important for late-stage morphological differentiation. In vitro mutational and genetic screening in Salmonella enterica serovar Typhimurium was performed in order to identify mutants with mutations in region 4 of sigma(28)(Ct) that were defective in sigma(28)-specific transcription. Specially,...

Read the complete abstract on PubMed

Topics

Amino Acid Sequence
Bacterial Proteins
Chlamydia trachomatis
DNA-Binding Proteins
DNA-Directed RNA Polymerases
Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutagenesis

Mutation

Promoter Regions, Genetic

Protein Binding

Sequence Alignment

Sigma Factor

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 18978051
DOI: 10.1128/JB.01083-08
PMCID: PMC2620819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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