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Article

Norepinephrine reversibly regulates the proliferation and phenotypic transformation of vascular smooth muscle cells.

Experimental and molecular pathology - 1 Dec 2008

Jiao Lei, Wang Min-Chen, Yang Ya-An, Chen Er-Qi, Xu Hong-Tao, Wu Kai-Yun, Zhang Shi-Ming

Abstract excerpt

OBJECTIVE: To investigate the effect of norepinephrine (NE) on the proliferation and phenotypic transformation of vascular smooth muscle cells (VSMCs) and the mechanisms underlying this effect. METHODS: VSMCs were isolated from the rat abdominal aorta. VSMCs cultured in both serum-containing or in a serum-free medium were treated with NE, oxidized low-density lipoprotein (ox-LDL), alpha-adrenergic receptor...

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PMID: 18976651
DOI: 10.1016/j.yexmp.2008.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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