Article
The clinical implications of HLA mismatches in unrelated donor haematopoietic cell transplantation.
International journal of immunogenetics - 1 Aug 2008
Shaw B E
Abstract excerpt
Haematopoietic stem cell transplantation (HSCT), using unrelated donors (UD), is now a common modality of treatment for individuals with a variety of different diseases. HLA matching has been shown to have a significant impact on patient outcome. This study includes 423 unrelated UK patient/donor pairs. The patients and donors were typed at high resolution for HLA-A, -B, -C, -DRB1, -DQB1, -DPB1. The degree and...
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