Article
Which factors influence the development of GVHD in HLA-matched or mismatched transplants?
Best practice & research. Clinical haematology - 1 Dec 2017
Petersdorf Effie W
Abstract excerpt
The sheer diversity of HLA alleles makes the probability of finding matched unrelated donors for patients requiring hematopoietic cell transplantation (HCT) a complex situation. New evidence suggests that mismatching at certain HLA loci may provide a greater benefit in terms of graft-versus-leukemia effect than other mismatches when HLA-matched donors are not available. This review summarizes the current...
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