Article
[Establishment of a pharmacogenomic testing system for the realization of individual pharmacotherapy].
Rinsho byori. The Japanese journal of clinical pathology - 1 Sept 2008
Yokota Hiromitsu, Satoh Yumiko, Ono Yoshikazu, Kaneko Makoto, Ikeda Hitoshi, Tsuji Shoji, Yatomi Yutaka
Abstract excerpt
The metabolism of and sensitivity to drugs differ from individual to individual, and one base polymorphism of drug-metabolizing enzymes is known to play an important role in this difference between individuals. The genotyping of drug-metabolizing enzymes prior to drug administration would help to predict individual reactivity to drugs and possible adverse reactions that may occur, which is essential to realize...
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