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Article

Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility.

Carcinogenesis - 1 Jan 2009

Ding Shian-Ling, Yu Jyh-Cherng, Chen Shou-Tung, Hsu Giu-Cheng, Kuo Shou-Jen, Lin Yu Hsin, Wu Pei-Ei, Shen Chen-Yang

Abstract excerpt

The role of the familial breast cancer susceptibility genes, BRCA1 and BRCA2, in the homologous recombination (HR) pathway for DNA double-strand break (DSB) repair suggests that the mechanisms involved in HR and DNA DSB repair are of etiological importance during breast tumorigenesis. Bloom (BLM)...

Read the complete abstract on PubMed

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Share to Breast Neoplasms
Share to BLM gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Rad51 Recombinase

Share to Recombination, Genetic

Share to RecQ Helicases

Source

Identifiers

PMID: 18974064
DOI: 10.1093/carcin/bgn233

Genes

RAD51
BLM
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18974064-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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