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Article

"Sequencing-grade" screening for BRCA1 variants by oligo-arrays.

Journal of translational medicine - 30 Oct 2008

Monaco Alessandro, Menolascina Filippo, Zhao Yingdong, Tommasi Stefania, Sabatino Marianna, Fasano Ross, Paradiso Angelo, Marincola Francesco M, Wang Ena

Abstract excerpt

The need for fast, efficient, and less costly means to screen genetic variants associated with disease predisposition led us to develop an oligo-nucleotide array-based process for gene-specific single nucleotide polymorphism (SNP) genotyping. This cost-effective, high-throughput strategy has high sensitivity and the same degree of accuracy as direct sequencing, the current gold standard for genetic screening. We...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome, Human

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Source

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Identifiers

PMID: 18973698
DOI: 10.1186/1479-5876-6-64
PMCID: PMC2583995

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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