Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reaction to succinylcholine in two patients segregating for the plasma cholinesterase allele Ek.

Acta anaesthesiologica Scandinavica - 1 Nov 1992

Jensen F S, Viby-Mogensen J

Abstract excerpt

Recently, several new alleles have been identified at plasma cholinesterase locus E1. We have had the opportunity for the first time to monitor the response to succinylcholine in two patients with the newly discovered genotype Ea1Ek1. The duration of action and type of neuromuscular block following succinylcholine 1.0 and 1.5 mg kg-1 i.v., respectively, were evaluated using train-of-four nerve stimulation and a...

Topics

Alleles
Cholinesterases
Edrophonium
Electric Stimulation
Female
Genotype
Humans
Injections, Intravenous
Muscle Contraction
Neuromuscular Junction
Pedigree
Reaction Time

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Succinylcholine

Synaptic Transmission

Ulnar Nerve

Source

Identifiers

PMID: 1334612
DOI: 10.1111/j.1399-6576.1992.tb03558.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1334612-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reaction to succinylcholine in two patients segregating for the plasma cholinesterase allele Ek.PMID 1334612Read ↗

Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years' experience with the Danish Cholinesterase Research Unit.Semantic proximity Read ↗

[Plasma cholinesterase and abnormal reaction to suxamethonium injection. 20-year experience with the Danish Cholinesterase Registry].Semantic proximity Read ↗

Prolonged response to succinylcholine: a new variant of plasma cholinesterase that is identified as normal by traditional phenotyping methods.Semantic proximity Read ↗

Pretreatment with pancuronium before suxamethonium administration in patients heterozygous for the usual and the atypical plasma cholinesterase gene.Semantic proximity Read ↗

Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine.Semantic proximity Read ↗

[Prolonged succinylcholine-induced apnoea associated with cholinesterase silent plasma variant].Semantic proximity Read ↗

Mivacurium-induced neuromuscular blockade in patients with atypical plasma cholinesterase.Semantic proximity Read ↗

Clinical importance of plasma cholinesterase for the anaesthetist.Semantic proximity Read ↗

Response to succinylcholine in patients carrying the K-variant of the butyrylcholinesterase gene.Semantic proximity Read ↗

Screening patients with prolonged neuromuscular blockade after succinylcholine and mivacurium.Semantic proximity Read ↗

[4 families with silent cholinesterase variant].Semantic proximity Read ↗

Identification of human plasma cholinesterase variants in 6,688 individuals using biochemical analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.