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Article

Analysis of the NRAMP1 gene implicated in iron transport: association with multiple sclerosis and age effects.

Blood cells, molecules & diseases - 1 Jan 2000

Kotze M J, de Villiers J N, Rooney R N, Grobbelaar J J, Mansvelt E P, Bouwens C S, Carr J, Stander I, du Plessis L

Abstract excerpt

Multiple sclerosis (MS) is believed to be an autoimmune process occurring in genetically susceptible individuals after an appropriate environmental exposure. We have exploited the homogeneous Afrikaner population of European ancestry to investigate the likelihood that iron dysregulation, in association with infectious and/or autoimmune disease susceptibility, may underlie the MS phenotype in a subgroup of...

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Identifiers

PMID: 11358358
DOI: 10.1006/bcmd.2000.0349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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