Article
No association between Fas A/G polymorphism and therapeutic effects induced by methimazole treatment for Graves' disease in Northern Chinese.
Die Pharmazie - 1 Oct 2008
Li Ping, Li Qiang, Chen Lili, Sun Yuquian, Zhang Jinchao
Abstract excerpt
Fas gene, which is related to apoptosis, influences the clinical remission of Graves' disease (GD). This study was performed to determine whether the Fas gene promoter polymorphism at position-670 is associated with different efficacy in GD patients treated with methimazole (MMI). Serum levels of thyroid hormone, sFas and thyrotropic-stimulating hormone receptor antibodies (TRAb) were evaluated as therapeutic...
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