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Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells

28 Oct 2008

Abstract excerpt

BACKGROUND: Bone marrow-derived mesenchymal stem cells (BMSCs) are a widely researched adult stem cell population capable of differentiation into various lineages. Because many promising applications of tissue engineering require cell expansion following harvest and involve the treatment of diseases and conditions found in an aging population, the effect of donor age and ex vivo handling must be understood in...

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PMID: 18957087
DOI: 10.1186/1471-2121-9-60

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