Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties.

doi:10.3389/fimmu.2019.02474

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Article

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties.

Frontiers in immunology - 1 Jan 2019

Andrzejewska Anastazja, Catar Rusan, Schoon Janosch, Qazi Taimoor Hasan, Sass Frauke Andrea, Jacobi Dorit, Blankenstein Antje, Reinke Simon, Krüger David, Streitz Mathias, Schlickeiser Stephan, Richter Sarina, Souidi Naima, Beez Christien, Kamhieh-Milz Julian, Krüger Ulrike, Zemojtel Tomasz, Jürchott Karsten, Strunk Dirk, Reinke Petra, Duda Georg, Moll Guido, Geissler Sven

Abstract excerpt

Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population. Currently, it is unclear whether advanced donor age and commonly associated comorbidities affect the properties of ex vivo-expanded BMSCs. Thus, we stratified cells from adult and...

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Identifiers

PMID: 31781089
DOI: 10.3389/fimmu.2019.02474
PMCID: PMC6857652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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