Article
Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice.
Journal of pediatric gastroenterology and nutrition - 1 Nov 2008
Ohlsson Lena, Hjelte Lena, Hühn Michael, Scholte Bob J, Wilke Martina, Flodström-Tullberg Malin, Nilsson Ake
Abstract excerpt
OBJECTIVES: The intestinal brush border enzymes alkaline sphingomyelinase (alk-SMase) and neutral ceramidase (CDase) digest milk sphingomyelin in suckling neonates. In addition, alk-SMase, CDase, and acid sphingomyelinase (acid-SMase) have been implicated in sphingolipid signaling, which exhibits...
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