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Article

Chronic treatment with melatonin attenuates serotonergic degeneration in the striatum and olfactory tubercle of zitter mutant rats.

Neuroscience letters - 26 Dec 2008

Ueda Shiuchi, Sakakibara Shin-Ichi, Kadowaki Taro, Naitoh Takuya, Hirata Koichi, Yoshimoto Kanji

Abstract excerpt

The effects of chronic treatment with the antioxidant hormone melatonin on degeneration of serotonergic fibers were studied in the striatum and olfactory tubercle of the zitter rat, which shows a loss-of-function mutation of the glycosylated transmembrane protein attractin. In these animals, serotonergic fibers in the striatum and olfactory tubercle undergo spontaneous and progressive degeneration as a result of...

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PMID: 18955113
DOI: 10.1016/j.neulet.2008.10.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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