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Article

Serotonin modulates circadian entrainment in Drosophila.

Neuron - 7 Jul 2005

Yuan Quan, Lin Fangju, Zheng Xiangzhong, Sehgal Amita

Abstract excerpt

Entrainment of the Drosophila circadian clock to light involves the light-induced degradation of the clock protein timeless (TIM). We show here that this entrainment mechanism is inhibited by serotonin, acting through the Drosophila serotonin receptor 1B (d5-HT1B). d5-HT1B is expressed in clock neurons, and alterations of its levels affect molecular and behavioral responses of the clock to light. Effects of...

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Identifiers

PMID: 15996552
DOI: 10.1016/j.neuron.2005.05.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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