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Article

The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan.

PLoS genetics - 1 Oct 2008

Collins James J, Evason Kimberley, Pickett Christopher L, Schneider Daniel L, Kornfeld Kerry

Abstract excerpt

Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide in lifespan extension is unknown, and eluc...

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PMID: 18949032
DOI: 10.1371/journal.pgen.1000230
PMCID: PMC2565500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18949032-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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