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Article

Association of Early Interferon‐γ Production with Immunity to Clinical Malaria: A Longitudinal Study among Papua New Guinean Children

23 Oct 2008

Abstract excerpt

BACKGROUND: Elucidating the cellular and molecular basis of naturally acquired immunity to Plasmodium falciparum infection would assist in developing a rationally based malaria vaccine. Innate, intermediate, and adaptive immune mechanisms are all likely to contribute to immunity. Interferon-gamma (IFN-gamma) has been implicated in both protection against and the pathogenesis of malaria in humans. In addition,...

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PMID: 18947328
DOI: 10.1086/592971

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