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Article

High frequency of genetic aberrations in enteropathy-type T-cell lymphoma.

Laboratory investigation; a journal of technical methods and pathology - 1 Oct 2003

Baumgärtner Anne K, Zettl Andreas, Chott Andreas, Ott German, Müller-Hermelink Hans Konrad, Starostik Petr

Abstract excerpt

To define genetic aberrations playing a role in the development of enteropathy-type T-cell lymphoma (ETL), we examined 26 such tumors using a battery of 47 microsatellite markers. The most frequent aberration (seen in 40% of informative genotypes) was amplification of genomic material in region 9q34 encompassing c-abl and Notch-1 gene loci. Other frequent amplifications were detected in regions 5q33.3-34 and 7q31...

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Share to Chromosome Aberrations
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Gene Rearrangement, T-Lymphocyte

Share to Intestinal Neoplasms

Share to Loss of Heterozygosity

Share to Lymphoma, T-Cell

Share to Microsatellite Repeats

Source

Identifiers

PMID: 14563952
DOI: 10.1097/01.lab.0000090157.13040.58

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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