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Article

TWEAK is expressed at the cell surface of monocytes during multiple sclerosis

22 Oct 2008

Abstract excerpt

The TNF superfamily ligand, TNF-like weak inducer of apoptosis (TWEAK), regulates cellular responses ranging from proliferation to cell death in a manner highly dependent on the cell type and the microenvironmental context. We have shown previously that treatment of experimental autoimmune encephalomyelitis mice after the priming phase with neutralizing anti-TWEAK antibodies results in a reduction in the severity...

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Identifiers

PMID: 18945822
DOI: 10.1189/jlb.0608347

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