Article
Expression of the endothelin axis in noninvasive and superficially invasive bladder cancer: relation to clinicopathologic and molecular prognostic parameters.
European urology - 1 Nov 2009
Eltze Elke, Wild Peter J, Wülfing Christian, Zwarthoff Ellen C, Burger Maximilian, Stoehr Robert, Korsching Eberhard, Hartmann Arndt
Abstract excerpt
BACKGROUND: The endothelin (ET) axis plays a role in cancer biology and plays a potential role as a target for molecular therapy in urogenital tumours. Alterations of several proteins of the ET axis were detected in invasive bladder cancer. OBJECTIVES: To examine the potential role of the expression of ET axis proteins compared to other prognostic parameters (kinase inhibitor 67 [Ki-67], tumour protein 53 [TP53],...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
