Article
Rapid genotypic assays to identify drug-resistant Mycobacterium tuberculosis in South Africa.
The Journal of antimicrobial chemotherapy - 1 Jan 2009
Evans Joanna, Stead Michael C, Nicol Mark P, Segal Heidi
Abstract excerpt
OBJECTIVES: Molecular assays to detect drug resistance in Mycobacterium tuberculosis are more rapid than standard drug susceptibility testing. To evaluate the efficacy of such assays in this setting, the GenoType MTBDRplus assay (HAIN Lifescience) and multiplex allele-specific PCR assays were carried out. METHODS: The GenoType MTBDRplus assay was evaluated for the detection of rifampicin and isoniazid resistance...
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