Article
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes.
Molecular cancer - 21 Oct 2008
Fan Teresa W M, Kucia Magda, Jankowski Kacper, Higashi Richard M, Ratajczak Janina, Ratajczak Marius Z, Lane Andrew N
Abstract excerpt
BACKGROUND: The functional status of a cell is expressed in its metabolic activity. We have applied stable isotope tracing methods to determine the differences in metabolic pathways in proliferating Rhabdomysarcoma cells (Rh30) and human primary myocytes in culture. Uniformly 13C-labeled glucose was used as a source molecule to follow the incorporation of 13C into more than 40 marker metabolites using NMR and...
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